BDBM434145 US10562891, Example 67::US11008308, Example 68

SMILES CN(C)C[C@H]1CC[C@H](CC1)SCc1nc2c(C)cccc2c(=O)[nH]1

InChI Key InChIKey=IFILIFYLYRJDSG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 434145   

TargetProtein mono-ADP-ribosyltransferase PARP14 [1611-1801](Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM434145(US10562891, Example 67 | US11008308, Example 68)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM434145(US10562891, Example 67 | US11008308, Example 68)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2021
Entry Details
Go to US Patent

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM434145(US10562891, Example 67 | US11008308, Example 68)
Affinity DataIC50: 5.50E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2021
Entry Details
Go to US Patent