BDBM434002 1-(4-(1H-pyrazol- 4-yl)phenyl)-4-(4- fluoro-3- methoxybenzyl)-3- methyl-1H-1,2,4-::US10562887, Example 121

SMILES COc1cc(Cn2c(C)nn(-c3ccc(cc3)-c3cn[nH]c3)c2=O)ccc1F

InChI Key InChIKey=HRYRPVVPPSOFER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 434002   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM434002(1-(4-(1H-pyrazol- 4-yl)phenyl)-4-(4- fluoro-3- met...)
Affinity DataIC50: 5nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL, assay containing 20 mM HEPES, pH 7.5, 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
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