BDBM433933 1-(4-(1H- pyrazol- 4-yl)phenyl)-4- (2-fluoro-3- methoxy- benzyl)-1H-::US10562887, Example 51

SMILES COc1cccc(Cn2cnn(-c3ccc(cc3)-c3cn[nH]c3)c2=O)c1F

InChI Key InChIKey=NRRTVUWZAKFUDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433933   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM433933(1-(4-(1H- pyrazol- 4-yl)phenyl)-4- (2-fluoro-3- me...)
Affinity DataIC50: 27.5nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL, assay containing 20 mM HEPES, pH 7.5, 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
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