BDBM433696 Preparation of 1-(4-(1H-pyrazol-4-yl)phenyl)-4-benzyl-1H-1,2,4-triazol-5(4H)-one::US10562887, Example 17

SMILES O=c1n(Cc2ccccc2)cnn1-c1ccc(cc1)-c1cn[nH]c1

InChI Key InChIKey=CHUAJBPDNHOOAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433696   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM433696(US10562887, Example 17 | Preparation of 1-(4-(1H-p...)
Affinity DataIC50: 27.5nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL, assay containing 20 mM HEPES, pH 7.5, 2...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2020
Entry Details
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