BDBM433600 5-[3-(1-Ethyl-3-methyl-1H-indol-2-yl)piperidine-1-carbonyl]-N-methylpyridazin-3-amine::US10562882, Example 18

SMILES CCn1c(C2CCCN(C2)C(=O)c2cnnc(NC)c2)c(C)c2ccccc12

InChI Key InChIKey=XIVUJUBBDPJNEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433600   

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM433600(US10562882, Example 18 | 5-[3-(1-Ethyl-3-methyl-1H...)
Affinity DataIC50: 2.17E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent