BDBM4336 2-[(5-hydroxy-2-nitrophenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 20

SMILES [#8]-c1ccc(c(\[#6]=[#6](/C#N)C#N)c1)-[#7+](-[#8-])=O

InChI Key InChIKey=NIFDXIKYQVKFBD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4336   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4336(2-[(5-hydroxy-2-nitrophenyl)methylidene]propanedin...)
Affinity DataKi:  2.40E+4nM ΔG°:  -6.23kcal/mole IC50: 9.60E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed