BDBM433428 US10562850, Compound 38d::US11066360, Compound 38d

SMILES CCC1(O)C[C@@H](N(C1)C(=O)OC(C)(C)C)C(=O)Nc1cc(ccc1F)C(CCC1CC1)(N[S@@](=O)C(C)(C)C)c1ccccn1

InChI Key InChIKey=LFTPBCWVQLYAOS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 433428   

TargetPlasma kallikrein(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM433428(US10562850, Compound 38d | US11066360, Compound 38...)
Affinity DataKi: <50nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates. In these experiments, 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetPlasma kallikrein(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM433428(US10562850, Compound 38d | US11066360, Compound 38...)
Affinity DataKi: <50nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
Go to US Patent