BDBM433348 US10561657, Example 28

SMILES OCc1nn(cc1-c1ncnc2[nH]ccc12)C(CC#N)C1CCCC1

InChI Key InChIKey=GPYUZESTZLMRNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433348   

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandPNGBDBM433348(US10561657, Example 28)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent