BDBM433345 US10561657, Example 26

SMILES NCCNC(=O)c1nn(cc1-c1ncnc2[nH]ccc12)C(CC#N)C1CCCC1

InChI Key InChIKey=XGXOYBSSTVJCCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433345   

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biophrama

US Patent
LigandPNGBDBM433345(US10561657, Example 26)
Affinity DataIC50: 20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent