BDBM433318 3-(ethylthio)-2-(4-(5-fluoropyridin-2-yl)benzyl)-5,7,7-trimethyl-7,8-dihydro-2H-imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(5H)-one::US10561656, Example 1

SMILES CCSc1c2c(nn1Cc1ccc(cc1)-c1ccc(F)cn1)N1CC(C)(C)N=C1N(C)C2=O

InChI Key InChIKey=QJODRMZIVBJSMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 433318   

LigandPNGBDBM433318(US10561656, Example 1 | 3-(ethylthio)-2-(4-(5-fluo...)
Affinity DataIC50: 2.70nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
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LigandPNGBDBM433318(US10561656, Example 1 | 3-(ethylthio)-2-(4-(5-fluo...)
Affinity DataIC50: 1.10E+4nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent