BDBM431874 US10550114, Compound 29

SMILES CN(CCc1ccc(cc1)N(C)C(=O)C=C)Cc1ccc(cc1)-c1nc2ccn(C)c(=O)c2cc1-c1ccccc1

InChI Key InChIKey=GXEALJGVCINJSV-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 431874   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431874(US10550114, Compound 29)
Affinity DataKd:  498nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431874(US10550114, Compound 29)
Affinity DataIC50: 249nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431874(US10550114, Compound 29)
Affinity DataIC50: 387nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase [E17K](Human)
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431874(US10550114, Compound 29)
Affinity DataIC50: 2.81E+4nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent