BDBM4315 (2E)-3-(3,4-dihydroxyphenyl)-2-[(4-phenylpiperazin-1-yl)carbonyl]prop-2-enenitrile::Tyrphostin deriv. 68

SMILES Oc1ccc(\C=C(/C#N)C(=O)N2CCN(CC2)c2ccccc2)cc1O

InChI Key InChIKey=LKHXJJMDMFKAPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4315   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4315((2E)-3-(3,4-dihydroxyphenyl)-2-[(4-phenylpiperazin...)
Affinity DataIC50: 4.30E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2005
Entry Details Article
PubMed