BDBM431068 6-[4-[(4-[[(2S,4R)-4-hydroxy-1-[6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-4-yl]pyrrolidin-2-yl]methoxy]cyclohexyl)carbonyl]piperazin-1-yl]pyridine-3-carbonitrile::US10550105, Example 52::US10870641, Example 52::US11014913, Example 52
SMILES O[C@@H]1C[C@@H](COc2cccc(c2)C(=O)N2CCN(CC2)c2ccc(cn2)C#N)N(C1)c1cn[nH]c(=O)c1C(F)(F)F
InChI Key InChIKey=CRVUUERXDVRKFW-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 431068
Affinity DataIC50: 100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair