BDBM430876 Example 12-A. tert-Butyl 4-(4-((7-(6-(4-(ethoxycarbonyl)-6-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-yl)indolin-1-yl)methyl)phenyl)piperidine-1-carboxylate::US10550102, Example 12

SMILES CCOC(=O)c1cnn(c1C(F)(F)F)-c1cccc(n1)-c1cccc2CCN(Cc3ccc(cc3)C3CCN(CC3)C(=O)OC(C)(C)C)c12

InChI Key InChIKey=QLTPBIHGEKOHBE-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430876   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Novartis

US Patent

LigandBDBM430876(Example 12-A. tert-Butyl 4-(4-((7-(6-(4-(ethoxycar...)Copy SMILESCopy InChI

Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2020
Entry Details
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