BDBM430678 Example 2-A. (+)-(S)-Ethyl-1-(3-(3-(4-(1-(cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenoxy)-2,3-dihydro-1H-inden-4-yl)phenyl)-6-methyl-1H-pyrazole-4-carboxylate::US10550102, Example 2

SMILES Cc1c(cnn1-c1cccc(c1)-c1cccc2CC[C@H](Oc3ccc(cc3C)C3CCN(CC3)C(=O)C3CC3)c12)C(O)=O

InChI Key InChIKey=WISJRAOXBPFAMB-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430678   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Novartis

US Patent

LigandBDBM430678(Example 2-A. (+)-(S)-Ethyl-1-(3-(3-(4-(1-(cyclopro...)Copy SMILESCopy InChI

Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2020
Entry Details
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