BDBM430282 US10556892, Compound 19::US10556892, Compound 8

SMILES CCS(=O)(=O)c1ccccc1C(=O)N2CCN(C[C@@H]2C)c3nc4ccc(cc4s3)F

InChI Key InChIKey=UKQOLPNYRVPCBM-UHFFFAOYSA-N

Data  6 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 430282   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of California

US Patent
LigandPNGBDBM430282(US10556892, Compound 8 | US10556892, Compound 19)
Affinity DataIC50: 500nMAssay Description:HEK293 cells stably transfected with the human NAAA coding sequence cloned from a human spleen cDNA library (catalog no. 639124, Clontech, Mountain V...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of California

US Patent
LigandPNGBDBM430282(US10556892, Compound 8 | US10556892, Compound 19)
Affinity DataIC50: 230nMAssay Description:HEK293 cells stably transfected with the human NAAA coding sequence cloned from a human spleen cDNA library (catalog no. 639124, Clontech, Mountain V...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of California

US Patent
LigandPNGBDBM430282(US10556892, Compound 8 | US10556892, Compound 19)
Affinity DataIC50: 554nMAssay Description:HEK293 cells stably transfected with the human NAAA coding sequence cloned from a human spleen cDNA library (catalog no. 639124, Clontech, Mountain V...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of California

US Patent
LigandPNGBDBM430282(US10556892, Compound 8 | US10556892, Compound 19)
Affinity DataIC50: 228nMAssay Description:HEK293 cells stably transfected with the human NAAA coding sequence cloned from a human spleen cDNA library (catalog no. 639124, Clontech, Mountain V...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of California

US Patent
LigandPNGBDBM430282(US10556892, Compound 8 | US10556892, Compound 19)
Affinity DataIC50: 230nMAssay Description:Inhibition of NAAA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
University of California

US Patent
LigandPNGBDBM430282(US10556892, Compound 8 | US10556892, Compound 19)
Affinity DataIC50: 230nMAssay Description:Inhibition of human NAAAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)