BDBM429588 US10550089, Example 62::US10995072, Example 62

SMILES Cn1ncc2c(F)ccc(C(O)c3ncc[nH]3)c12

InChI Key InChIKey=AMDDJWNWCHEAGY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 429588   

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429588(US10550089, Example 62 | US10995072, Example 62)
Affinity DataIC50: 1.23E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
Go to US Patent

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429588(US10550089, Example 62 | US10995072, Example 62)
Affinity DataIC50: 1.56E+4nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
Go to US Patent

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429588(US10550089, Example 62 | US10995072, Example 62)
Affinity DataIC50: 3.38E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
Go to US Patent