BDBM429450 6-(5- (cyclopropylcarbamoyl)- 3-fluoro-2- methylphenylN- cyclohexyl-N- methylpyridazin- 3-carboxamide::US10550073, Example 62

SMILES CN(C1CCCCC1)C(=O)c1ccc(nn1)-c1cc(cc(F)c1C)C(=O)NC1CC1

InChI Key InChIKey=KYEMULTYXJFIJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429450   

TargetMitogen-activated protein kinase 14(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM429450(6-(5- (cyclopropylcarbamoyl)- 3-fluoro-2- methylph...)
Affinity DataIC50: 100nMAssay Description:Experimental Method: 40 nM p38a was added into a reaction buffer, which include 20 mM HEPES (4-hydroxyethylpiperazine ethanesulfonic acid), 5 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
Go to US Patent