BDBM429436 N-cyclopropyl-3-fluoro- 5-(2-(isobutylamino) benzo[d]thiazol- 6-yl)-4-methylbenzamide::US10550073, Example 51

SMILES CC(C)CNc1nc2ccc(cc2s1)-c1cc(cc(F)c1C)C(=O)NC1CC1

InChI Key InChIKey=LVHXQMWHVLEBDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429436   

TargetMitogen-activated protein kinase 14(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM429436(N-cyclopropyl-3-fluoro- 5-(2-(isobutylamino) benzo...)
Affinity DataIC50: 550nMAssay Description:Experimental Method: 40 nM p38a was added into a reaction buffer, which include 20 mM HEPES (4-hydroxyethylpiperazine ethanesulfonic acid), 5 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
Go to US Patent