BDBM429434 N4'-cyclopentyl-N3- cyclopropyl-3',5- difluoro-6-methyl- [1,1'-biphenyl]-3,4'- dicarboxamide::US10550073, Example 32

SMILES Cc1c(F)cc(cc1-c1ccc(C(=O)NC2CCCC2)c(F)c1)C(=O)NC1CC1

InChI Key InChIKey=DTMOKADTOGQWJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429434   

TargetMitogen-activated protein kinase 14(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM429434(N4'-cyclopentyl-N3- cyclopropyl-3',5- difluoro-6-m...)
Affinity DataIC50: 100nMAssay Description:Experimental Method: 40 nM p38a was added into a reaction buffer, which include 20 mM HEPES (4-hydroxyethylpiperazine ethanesulfonic acid), 5 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
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