BDBM429432 N3-cyclopropyl-3',5- difluoro-N4'- isobutyl-6-methyl- [1,1'-biphenyl]-3,4'- dicarboxamide::US10550073, Example 30

SMILES CC(C)CNC(=O)c1ccc(cc1F)-c1cc(cc(F)c1C)C(=O)NC1CC1

InChI Key InChIKey=RGCWNSDXBXTUPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429432   

TargetMitogen-activated protein kinase 14(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM429432(N3-cyclopropyl-3',5- difluoro-N4'- isobutyl-6-meth...)
Affinity DataIC50: 100nMAssay Description:Experimental Method: 40 nM p38a was added into a reaction buffer, which include 20 mM HEPES (4-hydroxyethylpiperazine ethanesulfonic acid), 5 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
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