BDBM429306 acs.jmedchem.1c00409_ST.427::indole chloropyridinyl-ester derived, 7a::jm5b01461, Compound 126

SMILES Clc1cncc(OC(=O)c2ccc3[nH]ccc3c2)c1

InChI Key InChIKey=TYLOEMFGLQBHPE-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 429306   

TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM429306(jm5b01461, Compound 126 | indole chloropyridinyl-e...)
Affinity DataIC50: 310nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM429306(jm5b01461, Compound 126 | indole chloropyridinyl-e...)
Affinity DataEC50:  2.40E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM429306(jm5b01461, Compound 126 | indole chloropyridinyl-e...)
Affinity DataIC50: 310nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM429306(jm5b01461, Compound 126 | indole chloropyridinyl-e...)
Affinity DataEC50:  2.40E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM429306(jm5b01461, Compound 126 | indole chloropyridinyl-e...)
Affinity DataIC50: 310nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM429306(jm5b01461, Compound 126 | indole chloropyridinyl-e...)
Affinity DataEC50:  4.37E+4nMAssay Description:VeroE6 cells and TMPRSS2-overexpressing VeroE6 (VeroE6TMPRSS2) cells were obtained from the Japanese Collection of Research Bioresources (JCRB) Cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM429306(jm5b01461, Compound 126 | indole chloropyridinyl-e...)
Affinity DataIC50: 1.93E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed