BDBM429102 2-((3-cyano-8-methyl-4- (thiophen-2-yl)-5,6,7,8- tetrahydro-1,8-naphthyridin- 2-yl)thio)-2-phenylacetic acid::US10548313, Formula Ia-vi::US11375716, Formula Ia-vi

SMILES CN1CCCc2c1nc(SC(C(O)=O)c1ccccc1)c(C#N)c2-c1cccs1

InChI Key InChIKey=KPGGCLPRMJHOTM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 429102   

TargetAcetyl-CoA carboxylase(Maize)
Monsanto Technology

US Patent
LigandPNGBDBM429102(2-((3-cyano-8-methyl-4- (thiophen-2-yl)-5,6,7,8- t...)
Affinity DataIC50: 3.55E+3nMAssay Description:Ustilago maydis acetyl CoA carboxylase (ACCase) was cloned, expressed, and purified as described (Weatherly et al, Biochem. J., 2004) and the test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
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TargetAcetyl-CoA carboxylase(Corn smut fungus)
Monsanto Technology

US Patent
LigandPNGBDBM429102(2-((3-cyano-8-methyl-4- (thiophen-2-yl)-5,6,7,8- t...)
Affinity DataIC50: 3.55E+3nMAssay Description:In order to effectively screen out non-specific modulators of pyruvate kinase and lactate dehydrogenase (the coupled portion of the reaction), a PK/L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent