BDBM428864 US10533001, Example 1

SMILES NC(=O)c1cnc(On2nnc3ccccc23)nc1NC1CCC1

InChI Key InChIKey=GYQVSCUDTIJWHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 428864   

TargetTyrosine-protein kinase SYK(Human)
Portola Pharmaceuticals

US Patent
LigandPNGBDBM428864(US10533001, Example 1)
Affinity DataIC50: 55nMAssay Description:Syk and JAK: The activity of a specified compound as an inhibitor of a JAK kinase may be assessed in vitro or in vivo. In some embodiments, the activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent