BDBM428830 US20250092017, Compound P1

SMILES CC(C)c5ccc(N2CC1(CC(S(C)(=O)=O)C1)C2)c6ccc(Nc4ccnc(N3CCC(O)C(F)C3)n4)cc56

InChI Key InChIKey=HRWREZDQDUIZMQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 428830   

TargetEpidermal growth factor receptor(Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandPNGBDBM428830(US20250092017, Compound P1)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandPNGBDBM428830(US20250092017, Compound P1)
Affinity DataIC50: 2.78nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [L858R,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandPNGBDBM428830(US20250092017, Compound P1)
Affinity DataIC50: 58.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandPNGBDBM428830(US20250092017, Compound P1)
Affinity DataIC50: 0.470nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent