BDBM427318 (S)-2-((2-amino-2,4-dimethylpentyl)oxy)-5-(2-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzonitrile::US10544120, Example 328

SMILES CC(C)C[C@@](C)(COc1ccc(cc1C#N)-c1ccnc2[nH]c(C)cc12)NC(=O)OC(C)(C)C

InChI Key InChIKey=HEPMTGCGKVBUDH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427318   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427318(US10544120, Example 328 | (S)-2-((2-amino-2,4-dime...)
Affinity DataIC50: 0.400nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent