BDBM426809 US10544110, Compound JJ-450A

SMILES Cc1ccc(Cl)cc1N1CCN(CC1)C(=O)[C@H]1C[C@H]1c1ccc(F)cc1

InChI Key InChIKey=ITRMZYSEZBCBEC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426809   

TargetAndrogen receptor(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM426809(US10544110, Compound JJ-450A)
Affinity DataIC50: 1.60E+3nMAssay Description:The biological activity of analogs 5-16, 18, 20, 26, JJ-450, and the resolved enantiomers JJ-450A and J-450B was determined and compared to HTS hit 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM426809(US10544110, Compound JJ-450A)
Affinity DataEC50:  1.70E+3nMAssay Description:Antagonist activity at androgen receptor in human C4-2-PSA-rl cells incubated for 24 hrs in presence of androgen R1881 by dual-glo luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed