BDBM426705 N-(3-(6-(4-(pyrrolidine-1-carbonyl)phenyl) quinazolin-8-yl)phenyl)acrylamide::US10544106, Compound C102

SMILES C=CC(=O)Nc1cccc(c1)-c1cc(cc2cncnc12)-c1ccc(cc1)C(=O)N1CCCC1

InChI Key InChIKey=PTRAMKLVDLMSDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426705   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426705(N-(3-(6-(4-(pyrrolidine-1-carbonyl)phenyl) quinazo...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent