BDBM426696 4-(8-(1-acryloylpyrrolidin-3-yl)quinazolin-6-yl)- 3-chloro-N-(pyridin-2-yl)benzamide::US10544106, Compound C067

SMILES Clc1cc(ccc1-c1cc(C2CCN(C2)C(=O)C=C)c2ncncc2c1)C(=O)Nc1ccccn1

InChI Key InChIKey=RWVDWVCPLMTGAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426696   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426696(4-(8-(1-acryloylpyrrolidin-3-yl)quinazolin-6-yl)- ...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent