BDBM426689 1-(3-(6-(4-phenoxyphenyl)quinazolin-8- yl)pyrrolidin-1-yl)prop-2-en-1-one::US10544106, Compound C048

SMILES C=CC(=O)N1CCC(C1)c1cc(cc2cncnc12)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=SKOPZWHKGHSJQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426689   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426689(1-(3-(6-(4-phenoxyphenyl)quinazolin-8- yl)pyrrolid...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent