BDBM426666 4-[5-(3-fluoro-4-methoxy-phenyl)- 1-methyl-6-oxo-2-(piperidin-4- ylamino)-1,6-dihydro-pyrimidin-4-yl]- benzonitrile::US10543213, Example 48

SMILES COc1ccc(cc1F)-c1c(nc(NC2CCNCC2)n(C)c1=O)-c1ccc(CC#N)cc1

InChI Key InChIKey=QUPRFNOYNFAJED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426666   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM426666(4-[5-(3-fluoro-4-methoxy-phenyl)- 1-methyl-6-oxo-2...)
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
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