BDBM426313 US10513524, Compound (P3::US11608342, Compound (P3)::US20250019381, Compound (P3.1)

SMILES C[C@@H]1CN(Cc2ncccn2)C[C@H]1c1cn2c(ncc2c(=O)[nH]1)C1CCOCC1

InChI Key InChIKey=GWGNPYYVGANHRJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 426313   

LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 49nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent

LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 3.00E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent

LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 49nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 3.00E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of recombinant human PDE9A1 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 10nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 3.00E+3nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent