BDBM426302 6-(7-Morpholino-2-phenyl-pyrazolo[1,5-c]pyrimidin-3-yl)-3H-1,3-::US10513523, Example 242

SMILES O=c1[nH]c2ccc(cc2s1)-c1c(nn2c(nccc12)N1CCOCC1)-c1ccccc1

InChI Key InChIKey=XECHPRVQNPMNPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426302   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426302(US10513523, Example 242 | 6-(7-Morpholino-2-phenyl...)
Affinity DataIC50: 0.0500nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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