BDBM426293 4-[3-(1H-Indazol-5-yl)-2-phenyl-pyrazolo[1,5-c]pyrimidin-7-::US10513523, Example 233

SMILES C1CN(CCO1)c1nccc2c(c(nn12)-c1ccccc1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=VBAYEMYMNFMUOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426293   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426293(US10513523, Example 233 | 4-[3-(1H-Indazol-5-yl)-2...)
Affinity DataIC50: 0.400nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
Go to US Patent