BDBM426249 5-[7-(4-Methoxy-1-piperidyl)-2-phenyl-pyrazolo[1,5-c]pyrimidin-3-::US10513523, Example 189

SMILES COC1CCN(CC1)c1nccc2c(c(nn12)-c1ccccc1)-c1ccc2NC(=O)Cc2c1

InChI Key InChIKey=MUHYBAQMYXAFDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426249   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426249(US10513523, Example 189 | 5-[7-(4-Methoxy-1-piperi...)
Affinity DataIC50: 0.160nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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