BDBM426234 5-[2-(4-Fluorophenyl)-7-(4-oxo-1-piperidyl)pyrazolo[1,5-c]pyrimidin-3-::US10513523, Example 174

SMILES Fc1ccc(cc1)-c1nn2c(nccc2c1-c1ccc2NC(=O)Cc2c1)N1CCC(=O)CC1

InChI Key InChIKey=WZDTYLNITSQWCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426234   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426234(US10513523, Example 174 | 5-[2-(4-Fluorophenyl)-7-...)
Affinity DataIC50: 0.0800nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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