BDBM426174 5-(8-(4-Acetylpiperazin-1-yl)-2-benzyl-5-bromoimidazo[1,2-a]pyrazin-3-::US10513523, Example 113

SMILES CC(=O)N1CCN(CC1)c1ncc(Br)n2c(c(Cc3ccccc3)nc12)-c1ccc2NC(=O)Cc2c1

InChI Key InChIKey=OMKORJQNOVFGET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426174   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426174(US10513523, Example 113 | 5-(8-(4-Acetylpiperazin-...)
Affinity DataIC50: 0.320nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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