BDBM426138 5-[8-[4-(2-Fluoroethyl)-1-piperidyl]-2-phenyl-imidazo[1,2-a]pyrazin-3-::US10513523, Example 77

SMILES FCCC1CCN(CC1)c1nccn2c(c(nc12)-c1ccccc1)-c1ccc2NC(=O)Cc2c1

InChI Key InChIKey=IYGHATLDUFZHRF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426138   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426138(US10513523, Example 77 | 5-[8-[4-(2-Fluoroethyl)-1...)
Affinity DataIC50: 0.400nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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