BDBM426032 US10513518, Example 22

SMILES O[C@@H](CN1CCC2(CCN(C3=CS(=O)(=O)CC3)C2=O)CC1)c1ccc(nc1)-n1cnnn1

InChI Key InChIKey=KPVXKMCMWYWAPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426032   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM426032(US10513518, Example 22)
Affinity DataIC50: 114nMAssay Description:1. Seed HEK-hKir1.1 cells (50 μl at 20,000 cells/well) in 384-well PDL coated Microplates2. Allow cells to adhere overnight in humidified 37° C....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent