BDBM426022 US10513518, Example 12

SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(CN(C(=O)C2)C2=CC(=O)CC2)CC1

InChI Key InChIKey=KGFYUJBGFXMLCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426022   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM426022(US10513518, Example 12)
Affinity DataIC50: 521nMAssay Description:1. Seed HEK-hKir1.1 cells (50 μl at 20,000 cells/well) in 384-well PDL coated Microplates2. Allow cells to adhere overnight in humidified 37° C....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent