BDBM425881 N-hydroxy-2-[3'-(piperidin-1- ylmethyl)biphenyl-4-yl]-1H- benzimidazole-6-carboxamide trifluoroacetate::US10512634, Example 186

SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1cccc(CN2CCCCC2)c1

InChI Key InChIKey=TWRYORAOTHXDJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425881   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM425881(N-hydroxy-2-[3'-(piperidin-1- ylmethyl)biphenyl-4-...)
Affinity DataIC50: 4.10nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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