BDBM425880 2-(2-fluorobiphenyl-4-yl)-N- hydroxy-1H-benzimidazole- 6-carboxamide::US10512634, Example 180

SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(c(F)c1)-c1ccccc1

InChI Key InChIKey=IBLBPDCJZXPAIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425880   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM425880(2-(2-fluorobiphenyl-4-yl)-N- hydroxy-1H-benzimidaz...)
Affinity DataIC50: 19nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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