BDBM425877 2-[5-(2-fluorophenyl) thiophen-2-yl]- N-hydroxy-1H- benzimidazole-6-carboxamide::US10512634, Example 176

SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(s1)-c1ccccc1F

InChI Key InChIKey=OXKXISLGRRMLNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425877   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM425877(2-[5-(2-fluorophenyl) thiophen-2-yl]- N-hydroxy-1H...)
Affinity DataIC50: 2.90nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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