BDBM425249 4-[3-(1-allylpyrazol- 4-yl)-1-cyclopentyl- sulfonyl-pyrrolo[3,2-b] pyridin-6-yl]-3,5- dimethyl-isoxazole::US10519177, Compound P-0128

SMILES Cc1noc(C)c1-c1cnc2c(cn(c2c1)S(=O)(=O)C1CCCC1)-c1cnn(CC=C)c1

InChI Key InChIKey=XOJMEDGWRGCZSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425249   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425249(US10519177, Compound P-0128 | 4-[3-(1-allylpyrazol...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent