BDBM425232 3,5-dimethyl-4-[3-(1- methylpyrazol-4-yl)-1- propylsulfonyl-pyrrolo [3,2-b]pyridin-6- yl]isoxazole::US10519177, Compound P-0111

SMILES CCCS(=O)(=O)n1cc(-c2cnn(C)c2)c2ncc(cc12)-c1c(C)noc1C

InChI Key InChIKey=KQKZIXZRFQWCFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425232   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425232(US10519177, Compound P-0111 | 3,5-dimethyl-4-[3-(1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent