BDBM425191 4-[1-cyclohexyl- sulfonyl-3-[cyclopropyl (methoxy)methyl]pyrrolo [3,2-b]pyridin-6-yl]- 3,5-dimethyl-isoxazole::US10519177, Compound P-0071

SMILES COC(C1CC1)c1cn(c2cc(cnc12)-c1c(C)noc1C)S(=O)(=O)C1CCCCC1

InChI Key InChIKey=LBAQCVRAHJIZGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425191   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425191(US10519177, Compound P-0071 | 4-[1-cyclohexyl- sul...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
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Date in BDB:
10/19/2020
Entry Details
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