BDBM425182 3,5-dimethyl-4-[1- [(5-methyl-2-thienyl) sulfonyl]pyrrolo[3,2-b] pyridin-6-yl]isoxazole::US10519177, Compound P-0062

SMILES Cc1ccc(s1)S(=O)(=O)n1ccc2ncc(cc12)-c1c(C)noc1C

InChI Key InChIKey=MNSOQAPMLPNLKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425182   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425182(US10519177, Compound P-0062 | 3,5-dimethyl-4-[1- [...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
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