BDBM425165 4-[3-[(4,4-difluorocyclohexyl)- methoxy-methyl]-2-ethyl-1H- pyrrolo[2,3-b]pyridin-5-yl]-3,5- dimethyl-isoxazole::US10519177, Compound P-0045

SMILES CCc1[nH]c2ncc(cc2c1C(OC)C1CCC(F)(F)CC1)-c1c(C)noc1C

InChI Key InChIKey=MGRWKCBGPIGKQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425165   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425165(US10519177, Compound P-0045 | 4-[3-[(4,4-difluoroc...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
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