BDBM425154 4-[3-[(4,4-difluoro- cyclohexyl)methyl]-1H- pyrrolo[2,3-b]pyridin-5- yl]-3,5-dimethyl- isoxazole::US10519177, Compound P-0034

SMILES Cc1noc(C)c1-c1cnc2[nH]cc(CC3CCC(F)(F)CC3)c2c1

InChI Key InChIKey=JDRJBLWJWXHEAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425154   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425154(US10519177, Compound P-0034 | 4-[3-[(4,4-difluoro-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
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