BDBM425147 4-[3-[(2-chloro-6- fluoro-phenyl) methyl]-1H-pyrrolo [2,3-b]pyridin-5-yl]- 3,5-dimethyl-isoxazole::US10519177, Compound P-0027

SMILES Cc1noc(C)c1-c1cnc2[nH]cc(Cc3c(F)cccc3Cl)c2c1

InChI Key InChIKey=XPIGHEUHGMCQGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425147   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425147(US10519177, Compound P-0027 | 4-[3-[(2-chloro-6- f...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
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